To do what ‘104456’ is suggesting, right-click any blank space on your Desktop and select Properties. Click the Settings tab then the Advanced button. In the DPI setting pull-down, select the “Large size (120 DPI)” option then click Apply | OK.

If that still isn’t big enough, get back to the DPI setting pull-down, select “Custom setting...” and you can specify something larger. I know one guy that runs his at something close to 200%.

Note that when you run oversize like this though, some programs don’t display quite right. The wording and/or buttons may be partially hidden off the edges of the program windows.