okie dokie, just to update my progress; I've been able to successfully delete all 700+ infected files except for one, explore.exe *C:\WINDOWS\system32\explore.exe*.

After running the online virus scanner (housecall.trendmicro.com) and determining the folder in which the files were located, I was unable to delete them. Despite knowing the file name and pathway (eg. c:\my shared folder\Matchbox20 - unwell.exe), I couldn't manually locate the file in that particular folder. All that was there was the original mp3 (Matchbox20 - unwell.mp3).

So I cut and paste all files from My Shared Folder and temporarily stored it somewhere else, while deleting the empty My Shared Folder folder. When I ran the scanner again, all the 700+ infected files were gone except the one remaining "explore.exe *C:\WINDOWS\system32\explore.exe*".

I'm pretty sure I can't use the same technique, I'm afraid my comp will crash if I attempt to temporarily move system files.