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I agree there is no best. Over the last 3 to 5 years, I have tried most of the more popular AV's out. Most will stop much of the nasty garbage out there but not all. One thing I have decided is that black listing (which is mostly what AV's do) is ultimately the wrong approach. White listing/HIPS/software restriction policies/sand boxing, along with clean system images to restore back to are, IMO, the best ways to keep a Windows box clean. I still keep an AV on board but it's mostly out of habit, not for the core of my protection.
JPnyc: I'm surprised you didn't notice that new Eset NOD32 has both a dumbed down interface (the default) and a highly, more detailed than ever interface (that must be invoked by the user to see. And FWIW, I don't think KAV/KIS is the benchmark anymore. In fact, I don't think there is a benchmark anymore. Just a group of a half dozen or so that is decent protection.
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Well there are a few that are continually rated in the 98% detection rate, those being Kaspersky, Eset, and bit defender, most of the time.
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Anyone wanting Nortons Internet Security 2010 can pick up at Staples this week for $20 net after a $30 rebate. Incidentally, I received my cash rebate check from Nortons last week.