Scan it with your current a/v and let it delete or quarantine anything it finds then do a couple of online scans ...

http://www.pandasecurity.com/homeuse...s/activescan/?

http://www.ca.com/us/securityadvisor...info/scan.aspx

http://www.windowsecurity.com/trojanscan/

There have been some issues lately with the new housecall scan..

http://housecall.trendmicro.com/

I'd probably avoid this one.

I'm reasonably sure you can selectively scan a slave drive with these scanners.

So long as the slave drive isn't booted or any programs on it are run then no malware on it can do any damage on its own. A virus/trojan/etc would need to be activated by reinstalling it on the C drive or somehow be manually integrated into a running program.

Simply viewing the files on the slave drive is safe to do. Just don't open any executable files (exe, dll, com, pif, scr etc)

EDIT- doc and xls files can be risky too. Definately multi scan those at Jotti if you want to keep any.